structure of 1092578-46-5

3-((3R,4S)-4-Methyl-3-(Methyl(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)Amino)Piperidin-1-Yl)-3-Oxopropanenitrile(CAS 1092578-46-5)

CAS No.: 1092578-46-5 Brand: MolBest
M. Ft.: C16H20N6O Cat. No: G7471780
M. Wt.: 312.37 MDL: No record
Storage: Store in a cool,dry area. Use: For laboratory research use only
Purity Grade Package Stock Price Quantity
98%
Documents:COASDS
RG 1MG In Stock 61 USD
98%
Documents:COASDS
RG 5MG In Stock 84 USD
98%
Documents:COASDS
RG 25MG In Stock 337 USD
98%
Documents:COASDS
RG 100MG In Stock 1227 USD
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Applications of 1092578-46-5

Tofacitinib is primarily used for:

  • Rheumatoid Arthritis: Reduces symptoms and improves function in patients unresponsive to traditional therapies.
  • Psoriatic Arthritis: Alleviates joint pain and skin symptoms.
  • Ulcerative Colitis: Induces remission in patients with moderate to severe forms.
  • Polyarticular Course Juvenile Idiopathic Arthritis: Provides an alternative treatment option for children with this condition.

Physical and chemical properties of 1092578-46-5

Acidity coefficient

6.04±0.60(Predicted)

Boiling Point

585.8±50.0 °C at 760 mmHg

Density

1.3±0.1 g/cm3

Exact Mass

312.169861

Flash Point

308.1±30.1 °C

Index of Refraction

1.646

LogP

0.93

Melting Point

>108°C (dec.)

Molecular Formula

C16H20N6O

Molecular Weight

312.370

PSA

88.91000

Solubility

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)

Storage condition

-20°C

Vapour Pressure

0.0±1.6 mmHg at 25°C

Retrosynthesis analysis of 1092578-46-5

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