structure of 110351-91-2

(4R)-4-Ethyl-4-Hydroxy-7,8-Dihydro-1H-Pyrano[3,4-F]Indolizine-3,6,10(4H)-Trione(CAS 110351-91-2)

CAS No.: 110351-91-2 Brand: MolBest
M. Ft.: C13H13NO5 Cat. No: G4437760
M. Wt.: 263.25 MDL: No record
Storage: Store in a cool,dry area. Use: For laboratory research use only
Purity Grade Package Stock Price Quantity
95%
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RG 250MG In Stock 121 USD
95%
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RG 1G In Stock 278 USD
95%
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RG 5G In Stock 1387 USD
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Applications of 110351-91-2

The primary application of (R)-4-Ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione lies in its role as an intermediate in the synthesis of anticancer drugs. Specifically, it is utilized in producing camptothecin derivatives such as irinotecan and topotecan, which are widely used in chemotherapy for various cancers . Additionally, its unique structure may lead to further exploration in drug discovery for other therapeutic areas.

Physical and chemical properties of 110351-91-2

Acidity coefficient

11.20±0.20(Predicted)

Boiling Point

666.6±55.0 °C(Predicted)

Density

1.50±0.1 g/cm3(Predicted)

Exact Mass

263.07900

LogP

0.08910

Melting Point

169-170 °C(Solv: ethyl acetate (141-78-6))

Molecular Formula

C13H13NO5

Molecular Weight

263.25

PSA

85.60000

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H302 Harmful if swallowed

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