structure of 1380575-43-8

5-Chloro-N2-(2-Isopropoxy-5-Methyl-4-(Piperidin-4-Yl)Phenyl)-N4-(2-(Isopropylsulfonyl)Phenyl)Pyrimidine-2,4-Diamine Dihydrochloride(CAS 1380575-43-8)

CAS No.: 1380575-43-8 Brand: MolBest
M. Ft.: C28H38Cl3N5O3S Cat. No: G2704330
M. Wt.: 631.06 MDL: No record
Storage: 2-8°C,Under inert gas. Use: For laboratory research use only
Purity Grade Package Stock Price Quantity
98%
Documents:COANMRSDS
RG 100MG In Stock 29 USD
98%
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RG 250MG In Stock 67 USD
98%
Documents:COANMRSDS
RG 1G In Stock 203 USD
98%
Documents:COANMRSDS
RG 5G In Stock 472 USD
98%
Documents:COANMRSDS
RG 25G In Stock 2267 USD
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Applications of 1380575-43-8

Ceritinib dihydrochloride is primarily utilized in oncology for treating patients with advanced non-small cell lung cancer harboring ALK gene rearrangements. Its role as a second-generation ALK inhibitor makes it particularly valuable for patients who have developed resistance to first-line therapies like crizotinib. Beyond its primary application, ongoing research is exploring its potential effects on other signaling pathways involved in cancer progression and metabolic regulation.

Physical and chemical properties of 1380575-43-8

Exact Mass

629.176086

LogP

8.87040

Molecular Formula

C28H38Cl3N5O3S

Molecular Weight

631.057

PSA

116.85000

Storage condition

-20℃

Spectrums of 1380575-43-8

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 1380575-43-8

Retrosynthesis analysis of 1380575-43-8


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Operate under the ISO 9001 system