Ethyl 3,4-Difluorobenzoate(CAS 144267-96-9)
| Purity | Grade | Package | Stock | Price | Quantity |
| 98% | RG | 1G | In Stock | 5 USD
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| 98% | RG | 5G | In Stock | 5 USD
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| 98% | RG | 25G | In Stock | 15 USD
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| 98% | RG | 100G | In Stock | 31 USD
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| 98% | RG | 500G | In Stock | 148 USD
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| 98% | RG | 2.5KG | In Stock | 1169 USD
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| Bulk Packaging | 125KG | substantially lower unit cost than small-pack SKUs. Contact us for a fast quotation. | |||
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Your region is eligible for ordering. Available NMR Spectrum
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Quality System
Applications of 144267-96-9
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for synthesizing antitumor agents (e.g., BTK inhibitors) | Esterification or transesterification: refluxing 3,4-difluorobenzoic acid with ethanol under acid catalysis (e.g., concentrated sulfuric acid or p-toluenesulfonic acid); alternatively, acyl chloride route (activation with SOCl₂ followed by reaction with ethanol) |
| Pesticide R&D | Fluorinated structural motif for modifying agricultural fungicides and herbicides | Participates in nucleophilic substitution or palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to introduce fluorinated aryl fragments onto heterocyclic scaffolds |
| Organic Synthesis | Fluoroaryl building block for constructing liquid crystal materials and OLED functional molecules | Lithium–halogen exchange (using n-BuLi at low temperature) to generate aryllithium reagents, followed by addition to aldehydes/ketones or CO₂ trapping to yield carboxylic acid derivatives; alternatively, serves as substrate in Ullmann coupling |
Physical and chemical properties of 144267-96-9
Boiling Point |
223.4±25.0 °C at 760 mmHg |
|---|---|
Density |
1.2±0.1 g/cm3 |
Exact Mass |
186.049240 |
Flash Point |
86.6±18.1 °C |
Index of Refraction |
1.472 |
LogP |
2.97 |
Molecular Formula |
C9H8F2O2 |
Molecular Weight |
186.155 |
PSA |
26.30000 |
Storage condition |
Sealed in dry,Room Temperature |
Vapour Pressure |
0.1±0.4 mmHg at 25°C |
Spectrums of 144267-96-9
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Retrosynthesis analysis of 144267-96-9
Cas:64-17-5
Cas:455-86-7
Q&A for CAS 144267-96-9
1. How can I verify product quality?
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Yes. We support customization of Lab Grade purity, packaging size, and special testing requirements. Share your needs and we’ll provide a tailored solution.
10. Is the COA consistent with the shipped batch?
Yes. Batch COA available matches the actual shipment. COAs shown online are for reference or from previous batches.
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Yes. We offer Lab Supplier services for stable batch consistency, pricing agreements, and safety stock for long-term customers to ensure uninterrupted supply.
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Download SDS of 144267-96-9
Pictograms |
 |
|---|---|
Signal Word |
Warning |
Hazard Statements |
H302 Harmful if swallowed H312 Harmful in contact with skin H315 Causes skin irritation H319 Causes serious eye irritation H332 Harmful if inhaled H335 May cause respiratory irritation |
Safety Data Sheet |
Download COA of 144267-96-9
Operate under the ISO 9001 system
