structure of 298-46-4

Carbamazepine(CAS 298-46-4)

CAS No.: 298-46-4 Brand: MolBest
M. Ft.: C15H12N2O Cat. No: G7967218
M. Wt.: 236.27 MDL: MFCD00005073
Storage: Store under inert gas. Use: For laboratory research use only
HS CODE: 2933990090
Purity Grade Package Stock Price Quantity
99%
Documents:COANMRHPLCSDS
RG 5G In Stock 6 USD
99%
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RG 25G In Stock 12 USD
99%
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RG 100G In Stock 40 USD
99%
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RG 500G In Stock 175 USD
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RG 2.5KG In Stock 865 USD
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Applications of 298-46-4

Carbamazepine has several applications in medicine:

  • Epilepsy Treatment: It is effective in controlling various types of seizures.
  • Neuropathic Pain Management: It is used to alleviate pain associated with conditions like trigeminal neuralgia.
  • Bipolar Disorder: Carbamazepine is utilized in managing manic episodes and stabilizing mood .

Physical and chemical properties of 298-46-4

Boiling Point

399.6±45.0

Density

1.3±0.1 g/cm3

Exact Mass

236.094955

Flash Point

202.4±29.6 °C

Index of Refraction

1.670

LogP

2.3

Melting Point

190.2 °C

Molecular Formula

C15H12N2O

Molecular Weight

236.269

PSA

46.33000

Stability

To study the photostability of carbamazepine polymorphs, the pure materials on the tablet surface were evaluated without physical damage by means of Fourier-transform infrared reflection-absorption infrared spectrometry (FT-IR-RAS) and colorimetric measurement of the carbamazepine polymorphs I, II, and III, after photodegradation at 2 irradiation intensities under a near-UV fluorescent lamp. The surface of sample pellets of all crystalline forms turned gradually from white to yellow-orange upon exposure to light, and the discoloration rate of form II was faster than that of forms I and III, indicating that form II was the most unstable of the three. The semilogarithmic plots of the photodegradation profiles of the various polymorphs were straight lines, including the induction period, indicating that degradation of the drug on the surface followed first-order kinetics. The induction periods of all forms were not significantly different. However, the degradation rate constant of form II was 5.1 and 1.5 times larger than those of forms I and III, respectively.

Storage condition

2-8°C

Vapour Pressure

1.84X10-7 mm Hg at 25 °C (est)

Water Solubility

pract. insoluble

Spectrums of 298-46-4

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 298-46-4

Retrosynthesis analysis of 298-46-4


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Download SDS of 298-46-4

Pictograms

Signal Word

Danger

Hazard Statements

H302 Harmful if swallowed
H317 May cause an allergic skin reaction
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled

Safety Data Sheet

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