structure of 941678-49-5

Ruxolitinib(CAS 941678-49-5)

CAS No.: 941678-49-5 Brand: MolBest
M. Ft.: C17H18N6 Cat. No: G8349075
M. Wt.: 306.37 MDL: MFCD12031592
Storage: 2-8°C Use: For laboratory research use only
Purity Grade Package Stock Price Quantity
98%
Documents:COANMRLCMSSDS
RG 100MG In Stock 27 USD
98%
Documents:COANMRLCMSSDS
RG 250MG In Stock 31 USD
98%
Documents:COANMRLCMSSDS
RG 1G In Stock 84 USD
98%
Documents:COANMRLCMSSDS
RG 5G In Stock 292 USD
98%
Documents:COANMRLCMSSDS
RG 25G In Stock 2424 USD
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Applications of 941678-49-5

Ruxolitinib is primarily indicated for:

  • Myelofibrosis: It helps reduce spleen size and improve symptoms.
  • Polycythemia Vera: Used when patients do not respond adequately to hydroxyurea.
  • Graft-Versus-Host Disease: Effective in steroid-refractory cases following allogeneic stem cell transplantation.

Emerging research suggests potential applications in other conditions, including autoimmune diseases and certain types of cancer.

Physical and chemical properties of 941678-49-5

Acidity coefficient

11.63±0.50(Predicted)

Boiling Point

592.6±50.0 °C at 760 mmHg

Density

1.4±0.1 g/cm3

Exact Mass

306.159302

Flash Point

312.2±30.1 °C

Index of Refraction

1.747

LogP

log Kow = 2.09 (est)

Melting Point

84-89°C

Molecular Formula

C17H18N6

Molecular Weight

306.365

PSA

83.18000

Stability

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

Storage condition

2-8°C

Vapour Pressure

1.27X10-10 mm Hg at 25 °C (est)

Spectrums of 941678-49-5

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 941678-49-5

Retrosynthesis analysis of 941678-49-5

  • Route#1

    Cas:1236033-03-6
    Cas:941678-49-5
  • Route#2

    Cas:941685-40-1
    Cas:941678-49-5
  • Route#3

    Cas:941678-49-5

Q&A for CAS 941678-49-5

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Yes. Batch COA available matches the actual shipment. COAs shown online are for reference or from previous batches.

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Download SDS of 941678-49-5

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Signal Word

Warning

Hazard Statements

H361 Suspected of damaging fertility or the unborn child
H373 May causes damage to organs through prolonged or repeated exposure

Safety Data Sheet

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Operate under the ISO 9001 system